A magnitude 7.1 earthquake has jolted northwest China's Qinghai Province, killing at least 400 people, and injuring about 10-thousand others.

President Hu Jintao and Premier Wen Jiabao have ordered local authorities to make all-out efforts to save lives, and respond to the disaster. Vice Premier Hui Liangyu has rushed to the region as well.

Wednesday morning's earthquake struck Yushu county, located in one of Qinghai Province's five Tibetan Autonomous Prefectures.