America's three-time Wimbledon finalist Andy Roddick is likely to miss the French Open after he was forced to withdraw from the ATP tournament in Nice on Tuesday because of a shoulder injury.

The 28-year-old had been hoping to get a much-needed confidence boost after first-round exits on clay at both the Madrid and Rome Masters, but he conceded defeat and decided he would not be able to play his singles match on Wednesday against Romanian Victor Hanescu.

"I was already injured last week in Rome and I had to withdraw from the men's doubles final," said Roddick, whose best performance at Roland Garros was a fourth-round showing in 2009.

"I don't know yet if I will be able to play at Roland Garros and I think that you can't play a Grand Slam if you're not 100 percent," added Roddick, who is presently ranked 11th in the world.